名稱 | NRAS p.Q61L Reference Standard 標(biāo)準(zhǔn)品 |
型號 | CBP10311 |
報(bào)價(jià) | |
特點(diǎn) | NRAS p.Q61L Reference Standard |
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基因檢測標(biāo)準(zhǔn)品 > Mutation > CBP10311NRAS p.Q61L Reference Standard 標(biāo)準(zhǔn)品
- 詳細(xì)內(nèi)容
CBP10311 | |
Format | Genomic DNA |
Description | NRAS Q61L is a hotsopt mutation that lies within a GTP-binding region of the Nras protein (UniProt.org). Q61L confers a loss of function on Nras protein as indicated by increase Erk and Mek phosphorylation, and activation of Ck2alpha in cell culture (PMID: 27251789). |
Technical Data | |
DNA Change | c.182A>T |
AA Change | p.Q61L |
Mutation type | Substitution - Missense |
Zygosity | Homozygous |
Allelic Frequency | 100% |
Transcript | ENST00000369535 |
Cosmic ID | COSM583 |
Chr position(GRCh37) | chr1:115256529 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |