| 名稱 | TP53 p.D281G Reference Standard 標(biāo)準(zhǔn)品 |
| 型號(hào) | CBP10210 |
| 報(bào)價(jià) |  |
| 特點(diǎn) | TP53 p.D281G Reference Standard |
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基因檢測標(biāo)準(zhǔn)品 > Mutation > CBP10210TP53 p.D281G Reference Standard 標(biāo)準(zhǔn)品
- 詳細(xì)內(nèi)容
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CBP10210 | |
| Format | Genomic DNA |
| Description | TP53 D281G lies within the DNA interaction domain of the Tp53 protein (UniProt.org). The functional effect of D281G is conflicting, as it has been reported to decrease transactivation of wild-type Tp53 targets and also confers a gain of function to Tp53, which leads to aberrant gene transcription and cell migration (PMID: 22114072). |
| Technical Data | |
| DNA Change | c.842A>G |
| AA Change | p.D281G |
| Mutation type | Substitution - Missense |
| Zygosity | Homozygous |
| Allelic Frequency | 100% |
| Transcript | ENST00000269305 |
| Cosmic ID | COSM11232 |
| Chr position(GRCh37) | chr17:7577096 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing | Download for COA |
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
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