名稱 | TP53 p.Y220C Reference Standard 標(biāo)準(zhǔn)品 |
型號(hào) | CBP10144 |
報(bào)價(jià) | ![]() |
特點(diǎn) | TP53 p.Y220C Reference Standard |
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Email: zhangxiangwen@cobioer.com
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基因檢測(cè)標(biāo)準(zhǔn)品 > Mutation > CBP10144TP53 p.Y220C Reference Standard 標(biāo)準(zhǔn)品

- 詳細(xì)內(nèi)容
CBP10144 | |
Format | Genomic DNA |
Description | TP53 Y220C is a hotspot mutation that lies within the DNA-binding domain (PMID: 17401432). Y220C is predicted to confer a loss of function to the Tp53 protein, as demonstrated by decreased Tp53 transcriptional activity in cell culture (PMID: 16861262, PMID: 23630318). |
Technical Data | |
DNA Change: | c.659A>G |
AA Change | p.Y220C |
Mutation type | Substitution - Missense |
Zygosity | Homozygous |
Allelic Frequency | 100% |
Transcript | ENST00000269305 |
Cosmic ID | COSM10758 |
Chr position(GRCh37) | chr17:7578190 |
Buffer: | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |