| 名稱 | PIK3CA p.G118D Reference Standard 標(biāo)準(zhǔn)品 |
| 型號(hào) | CBP10327 |
| 報(bào)價(jià) |  |
| 特點(diǎn) | PIK3CA p.G118D Reference Standard 標(biāo)準(zhǔn)品 |
產(chǎn)品搜索
相關(guān)文章
- 為您解讀ATCC細(xì)胞株的可追溯性
- 增強(qiáng)腫瘤免疫療法新靶點(diǎn)：ADORA2B（腺苷A2B受體）
- 自身免疫疾病潛力靶點(diǎn)——IL-5藥篩細(xì)胞模型
- IHC第三方質(zhì)控品——病理質(zhì)控基石，精準(zhǔn)診斷起點(diǎn)
- 對(duì)ATCC細(xì)胞培養(yǎng)時(shí)的試劑有何要求？
- PD-1/L1 &4-1BB雙靶點(diǎn)細(xì)胞篩選模型
- 大腦中新發(fā)現(xiàn)的一種淋巴細(xì)胞，能夠清除大腦廢物
- 上海細(xì)胞庫(kù)——南京科佰生物
- 【新品上線】一種安全高效的中和抗體體外篩選模型
- 是激活還是沉默？基因表達(dá)的新路徑
聯(lián)系我們
聯(lián)系人：蔣經(jīng)理
電話：4008750250
號(hào)碼：
手機(jī)：18066071954
地址：南京市棲霞區(qū)緯地路9號(hào)
Email： zhangxiangwen@cobioer.com
電話：4008750250
號(hào)碼：
手機(jī)：18066071954
地址：南京市棲霞區(qū)緯地路9號(hào)
Email： zhangxiangwen@cobioer.com
產(chǎn)品展示 / PRODUCTS
基因檢測(cè)標(biāo)準(zhǔn)品 > Mutation > CBP10327PIK3CA p.G118D Reference Standard 標(biāo)準(zhǔn)品
- 詳細(xì)內(nèi)容
" _ue_custom_node_="true">
CBP10327 | |
| Format | Genomic DNA |
| Description | PIK3CA G118D lies within the region linking the PI3K-ABD and PI3K-RBD domains of the Pik3ca protein (UniProt.org). G118D confers a gain of function on the Pik3ca protein as indicated by enhanced lipid kinase activity in cell culture, increased phosphorylation of Akt in cells derived from Cowden syndrome patients harboring germline mutations (PMID: 22949682, PMID: 23246288), and increased transformation ability in two different cell lines (PMID: 29533785). |
| Technical Data | |
| DNA Change | c.353G>A |
| AA Change | p.G118D |
| Mutation type | Substitution - Missense |
| Zygosity | Heterozygous |
| Allelic Frequency | 75.00% |
| Transcript | NM_006218.1 |
| Cosmic ID | COSM751 |
| Chr position(GRCh37) | chr3:178917478 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |
|
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
會(huì)員_a.png)