名稱(chēng) | AI-Edigene® EGFR p.C797S 標(biāo)準(zhǔn)品 |
型號(hào) | CBP10341 |
報(bào)價(jià) | ![]() |
特點(diǎn) | AI-Edigene® EGFR p.C797S 標(biāo)準(zhǔn)品 |
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電話:4008750250
號(hào)碼:
手機(jī):18066071954
地址:南京市棲霞區(qū)緯地路9號(hào)
Email: zhangxiangwen@cobioer.com
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基因檢測(cè)標(biāo)準(zhǔn)品 > Mutation > CBP10341AI-Edigene® EGFR p.C797S 標(biāo)準(zhǔn)品

- 詳細(xì)內(nèi)容
CBP10341 | |
Format | Genomic DNA |
Description | EGFR C797S lies within the ATP-binding pocket in the protein kinase domain of the Egfr protein (PMID: 25964297). C797S has been demonstrated to confer resistance to third-generation EGFR inhibitors (PMID: 25964297, PMID: 25948633, PMID: 29410323), but has not been biochemically characterized and therefore, its effect on Egfr protein function is unknown (PubMed, Jun 2018). |
Technical Data | |
DNA Change: | c.2389T>A |
AA Change | p.C797S |
Mutation type | Substitution - Missense |
Zygosity | Heterozygous |
Allelic Frequency | 50% |
Transcript | ENST00000275493 |
Chr position(GRCh37) | COSM6493937 |
Chr position(GRCh37) | chr7:55249091 |
Buffer: | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1µg |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |