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藥靶細胞株 > kinase激酶細胞株 > CBP73227KRAS G12C/BaF3

KRAS G12C/BaF3
名稱 KRAS G12C/BaF3
型號 CBP73227
報價
特點 KRAS G12C/BaF3,母細胞:BaF3,凍存條件:90% FBS+10% DMSO
  • 詳細內容


CBP73227
I. Introduction

Cell Line Name:

KRAS G12C/BaF3

Host Cell:

Ba/F3

Stability:16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)

Application:

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.

Freeze Medium:

90% FBS+10% DMSO

Complete Culture Medium:

RPMI-1640+10%FBS+1ug/ml puromycin

Mycoplasma Status:

Negative

II.Background

KRAS, KRAS proto-oncogene, GTPase, is a member of the small GTPase superfamily and a key regulator of the MAPK, PI3K/AKT/mTOR pathways (PMID: 23622131). KRAS mutations are identified in a wide range of cancers (PMID: 28666118).

III. Representative Data

1.WB of KRAS G12C/BaF3

CBP73227 WB.png


2.Sanger of KRAS G12C/BaF3

CBP73227 sanger.png


3. Anti-proliferation assay

Figure 3. CTG Proliferation Assay of BaF3 KRAS G12C Cells (C3).





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