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藥靶細胞株 > GPCR細胞株 > CBP71376EDNRB/β-Arrestin/CHO GPCR細胞

EDNRB/β-Arrestin/CHO GPCR細胞
名稱 EDNRB/β-Arrestin/CHO GPCR細胞
型號 CBP71376
報價
特點 EDNRB/β-Arrestin/CHO
  • 詳細內(nèi)容
CBP71376
I. Background
EDNRB (Endothelin Receptor Type B) is a Protein Coding gene. Diseases associated with EDNRB include Waardenburg Syndrome, Type 4A and Abcd Syndrome. Among its related pathways are Class A/1 (Rhodopsin-like receptors) and Endothelins. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and type 1 angiotensin receptor binding.

II. Introduction
Host Cell:

CHO

Stability:20 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Freeze Medium:90% FBS+10% DMSO
Culture Medium:F12K+10%FBS+5ug/ml puromycin+5ug/ml blasticidin
Mycoplasma Status:Negative
Storage:Liquid nitrogen immediately upon delivery
Application(s):

Functional assay for EDNRB receptor

Transducer:Activation of ETB receptors to produce a range of biological actions in different tissues is thought to be mediated by a number of transduction systems coupled to various types of G-protein including Gq/G11, Gs, Gq/13 and Gi2.

Ⅲ. Description of Host Cell Line
Organism:Hamster
Tissue:Ovary
Morphology: Epithelial
Growth Properties: Adherent

Ⅳ. Representative Data

Figure 1.Recombinant EDNRB/β-Arrestin/CHO constitutively expressing EDNRB/β-Arrestin.

Figure 2. Dose response of Endothelin 3 (human,mouse,rabbit, rat TFA) in CHO-K1 EDNRB(ET2,ETB) β-Arrestin Cell line(C11).


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