| 名稱 | EZH2 p.A682G Reference Standard 標(biāo)準(zhǔn)品 |
| 型號 | CBP10559 |
| 報價 |  |
| 特點 | EZH2 p.A682G Reference Standard |
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基因檢測標(biāo)準(zhǔn)品 > Mutation > CBP10559EZH2 p.A682G Reference Standard 標(biāo)準(zhǔn)品
- 詳細(xì)內(nèi)容
CBP10559 | |
| Format | Genomic DNA |
| Description | EZH2, enhancer of zeste 2 polycomb repressive complex 2 subunit, encodes the catalytic subunit of the polycomb repressive complex 2, which methylates histone H3 to represses gene transcription, including a number of tumor suppressor genes (PMID: 24362326, PMID: 30112706). EZH2 mutations and overexpression has been observed in a variety of tumor types, including non-Hodgkin lymphoma (PMID: 30112706), leukemia (PMID: 29289837), and ovarian cancer (PMID: 29726819). |
| Technical Data | |
| DNA Change | c.2045C>G |
| AA Change | p.A682G |
| Mutation type | Substitution - Missense |
| Zygosity | Heterozygous |
| Allelic Frequency | 50% |
| Transcript | NM_004456.5 |
| Cosmic ID | COSM220386 |
| Chr position(GRCh37) | chr7:148506467 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |
|
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
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