| 名稱(chēng) | AI-Edigene® FLT3 p.D835Y Reference Standard P |
| 型號(hào) | CBP10499 |
| 報(bào)價(jià) |  |
| 特點(diǎn) | AI-Edigene® FLT3 p.D835Y Reference Standard Plus |
產(chǎn)品搜索
產(chǎn)品分類(lèi)
相關(guān)文章
- 鑒別出促進(jìn)黑色素瘤進(jìn)展的關(guān)鍵蛋白,開(kāi)發(fā)出新型癌癥靶向療法
- 【靶點(diǎn)模型+診斷質(zhì)控】FLT3-ITD的藥物開(kāi)發(fā)和診斷
- Z常用細(xì)胞系之top 5！
- 你知道ATCC細(xì)胞如何解凍嗎？
- 你見(jiàn)過(guò)低至6000元，還贈(zèng)對(duì)照的慢病毒包裝嗎？
- 細(xì)胞株開(kāi)發(fā)的主要過(guò)程要知道
- IL27細(xì)胞篩選模型
- AVβ6靶點(diǎn)細(xì)胞篩選模型
- 【產(chǎn)品推介】CD47&SIRPɑ 細(xì)胞篩選模型
- 細(xì)胞株的核型分析實(shí)驗(yàn)操作流程分析
聯(lián)系我們
聯(lián)系人：蔣經(jīng)理
電話(huà)：4008750250
號(hào)碼：
手機(jī)：18066071954
地址：南京市棲霞區(qū)緯地路9號(hào)
Email： zhangxiangwen@cobioer.com
電話(huà)：4008750250
號(hào)碼：
手機(jī)：18066071954
地址：南京市棲霞區(qū)緯地路9號(hào)
Email： zhangxiangwen@cobioer.com
產(chǎn)品展示 / PRODUCTS
基因檢測(cè)標(biāo)準(zhǔn)品 > Mutation > CBP10499AI-Edigene® FLT3 p.D835Y Reference Standard P
- 詳細(xì)內(nèi)容
CBP10499 | |
| Format | Genomic DNA |
| Description | FLT3 D835Y lies within the protein kinase domain activation loop of the Flt3 protein (UniProt.org, PMID: 11290608). D835Y results in constitutive phosphorylation of Flt3 and activation of Stat5, Erk signaling, leading to transformation of cultured cells (PMID: 15256420, PMID: 30651561), and has been demonstrated to promote secondary drug resistance in the context of FLT3 internal tandem duplication (FLT3-ITD) mutations (PMID: 22504184, PMID: 29187377). |
| Technical Data | |
| DNA Change | c.2503G>T |
| AA Change | p.D835Y |
| Mutation type | Substitution - Missense |
| Zygosity | Homozygous |
| Allelic Frequency | 100% |
| Transcript | NM_004119.3 |
| Cosmic ID | COSM783 |
| Chr position(GRCh37) | chr13:28592642 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |
|
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
會(huì)員_a.png)