名稱(chēng) | CYP2D6*10 Reference Standard |
型號(hào) | CBPA0072 |
報(bào)價(jià) | |
特點(diǎn) | CYP2D6*10 Reference Standard |
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電話:4008750250
號(hào)碼:
手機(jī):18066071954
地址:南京市棲霞區(qū)緯地路9號(hào)
Email: zhangxiangwen@cobioer.com
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基因檢測(cè)標(biāo)準(zhǔn)品 > 用藥指導(dǎo) > CBPA0072CYP2D6*10 Reference Standard
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CBPA0072 | |
Format | Genomic DNA |
Description | CYP2D6, cytochrome P450 family 2 subfamily D member 6, is a member of the cytochrome P450 family of monooxygenases that catalyzes drug metabolism (PMID: 28480783). CYP2D6 variants have been associated with risks of various cancers (PMID: 22994728, PMID: 16550168) and may alter the metabolism of tamoxifen in breast cancer patients. |
Technical Data | |
Gene | CYP2D6 |
Mutation Type 1 | AA Change: p.S486T |
DNA Change: NM_000106.6:c.1457G>C | |
Chr position (GRCh38): chr22:42126611 | |
Mutation Type 2 | AA Change: p.P34S |
DNA Change: NM_000106.6:c.100C>T | |
Chr position (GRCh38): chr22:42130692 | |
Allelic Frequency | 100% |
Zygosity | Homozygous |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | Figure 1. CYP2D6*10 Reference Standard p.S486T Figure 2. CYP2D6*10 Reference Standard p.P34S |
Storage | 4°C |
Expiry | 36 months from the date of manufacture |